Introduction to Upcon® Technology
Upcon® Technology
How does the highly sensitive Uniogen Upcon® upconverting nanoparticle technology work?
Upcon® Nanoparticles
High-quality UCNPs for various applications. Pick the most optimal combination for your application!
Why Choose Upcon®?
- No photobleaching or self-Quenching thanks to highly stable upconverting nanoparticles
- Virtually zero autofluorescence enabling low-background detection
- Bright, discrete emission bands for clean and reliable signal separation
- Clear signal even through challenging sample matrices, such as tissue and whole blood
- Consistent, quantitative performance suitable for research, diagnostics, and imaging
- Guaranteed Quality and possibility for ISO13485 certified production
Where Upcon® Excels?
Upcon® technology is highly versatile and supports:
- Point-of-Care testing
- Veterinary testing
- Food safety testing
- Environmental monitoring
- Imaging applications
…all with enhanced sensitivity and reduced background noise.
Try Upcon® technology in your application!
Uniogen offers a complete technology evaluation service, making it easy for you to explore the benefits of UCNPs without any upfront commitment.
- No instrument or reagent investment needed until you see the technology works
- Reliable quality control following established and validated procedures
- Comprehensive reporting, including results and an expert review session with our team
If in‑house testing is preferred, the evaluation can also be carried out at your own facilities. Uniogen will provide support, guidance, and expertise whenever needed
Contact us to get started!
1. Technology Evaluation
Choose your Upcon® particle type and binder
Let us do the conjugation and testing, or test in your own lab
2. Assay Development
Let us set up and optimize your assay according to your specifications
Or lease our reader device and do the assay development step yourself. We’ll help you if needed!
3. Assay Validation
Send your samples for analytical performance evaluation
Or do it in your own lab
4. Scale-up
Transfer to production, batch release testing, and clinical validation with multiple lots
Or customized OEM plan
Uniogen’s Upcon nanoparticle technology fuels the superior sensitivity in Lumito’s game-changing histopathology product
Lumito, a leading medical technology company focuses tissue analysis and digital pathology. Their proprietary technology, generating high-definition images enables high sensitivity and quantitative measurement of biomarkers in tissue. Lumito’s solution, Scizys, is primarily targeting pharmaceutical development and research to enable faster and more effective development of new drugs.
“Collaborating with Uniogen to deliver next generations tissue analysis is a true pleasure. Their skilled and experienced team, covering research to product development and manufacturing, is both flexible and always willing to support. This is crucial for us, being new in the market, and in the early commercialization phase.”
Sanna Wallenborg, CEO
Lumito AB
Upcon® – Frequently Asked Questions
Upcon® upconverting nanoparticle technology is a labeling and signal‑generation technology used for sensitive optical detection in diagnostic and life science applications. It enables the generation of a measurable luminescence signal and is commonly applied in immunoassays, imaging, and other analytical formats used in diagnostics, life science research, and assay development. By providing reliable signal detection across different applications, Upcon® supports both research and applied testing workflows.
Upcon® upconverting nanoparticle technology addresses key challenges in diagnostic and life science applications related to sensitivity and analytical reliability. It enables high‑sensitivity detection even in complex or challenging sample matrices, where background interference or low analyte concentrations can limit the performance of conventional detection methods. By improving signal quality and measurement robustness, Upcon® supports more reliable quantitative analysis across a range of assay formats.
Upcon® upconverting nanoparticle technology is designed to be used by both researchers and biotechnology companies. It is suitable for research and assay development approaches, and can be integrated as a part of commercial products.
Upcon® upconverting nanoparticle technology is well suited for a wide range of diagnostic and analytical applications where high sensitivity and quantitative performance are required. Typical applications include point‑of‑care testing, clinical and veterinary diagnostic assays, food and environmental safety testing, as well as imaging‑based applications.
Upcon® technology is especially effective in quantitative lateral flow immunoassays, where its unique optical properties enable sensitive and reliable signal detection, even at low analyte concentrations.
Yes. Measurement of up‑conversion luminescence from Upcon® nanoparticles requires a dedicated reader equipped with near‑infrared (NIR) laser excitation. Uniogen offers Upcon® reader devices specifically designed for this purpose, supporting both microplate scanning and simultaneous readout of multiple lateral flow strips.
For applications requiring flexibility or field use, a compact and portable lateral flow strip reader is available, enabling reliable detection also outside traditional laboratory settings.
Yes. Uniogen provides technical support and application assistance for Upcon® users throughout the entire process, from initial evaluation to workflow integration and routine use. Our experts support customers in selecting, implementing, and optimizing Upcon® technology to ensure reliable performance in their specific application.
With over 20 years of experience in upconverting nanoparticle technology, Uniogen’s team offers long‑term support to help users confidently adopt and maintain Upcon® as part of their workflows.